Zoledronic Acid (Zometa, Reclast)
Dosage form:
Injectable: ready-to-use solution 4 mg/100 mL, or concentrate 4 mg/5 mL requiring dilution.
Pharmacological group:
Bisphosphonate (bone metabolism modifier)
Therapeutic use:
Reduction of refractory hypercalcemia. Reduction of pain associated with osteolytic conditions (e.g., bone tumors).
Dosage:
Dogs:
0.1–0.25 mg/kg slowly intravenously in 100 mL (50 mL for small dogs) of 0.9% normal saline over 15–30 minutes. Some sources recommend a maximum total dose of 4 mg; doses at the lower end of the range are generally preferred. Pre- and post-infusion hydration with 0.9% saline over 30 minutes may prevent nephrotoxicity. May be repeated as clinically necessary, but no more often than every 4 weeks.
Calculate medication dosage for pets
Zoledronic Acid (Zometa, Reclast) dosage calculation
Accurate dosing is essential when treating pets. To calculate a single dose correctly, you need three key values: the animal’s weight, the required dose of the active ingredient, and the concentration of the medication.
Calculation formula:
Single dose = (Animal weight × Required dose) ÷ Medication concentration
Important notes:
- Always consult a veterinarian before using any medication.
- Follow the recommended dosage and instructions for use.
Accurate dosing helps protect your pet’s health and reduces the risk of side effects.