Vitamin K1 (Phytonadione, Phytomenadione) (Mephyton, Aquamephyton)
Dosage form:
Injectable solution 10 mg/mL; tablets 50 mg
Pharmacological group:
Vitamins
Therapeutic use:
Rodenticide (anticoagulant) poisoning; coagulopathy; vitamin K1 deficiency
Dosage:
Dogs:
First-generation rodenticide poisoning or K1 deficiency: starting dose 2.5 mg/kg subcutaneously or intramuscularly, then 1–2.5 mg/kg orally in divided doses every 8–12 hours for 5–7 days.
Second-generation rodenticide poisoning: starting dose 5 mg/kg subcutaneously or intramuscularly, then 2.5 mg/kg subcutaneously every 12 hours for 3 weeks, then reassess coagulation status.
Unknown rodenticide or indandione poisoning: starting dose 2.5–5 mg/kg subcutaneously or intramuscularly, then 2.5 mg/kg orally in divided doses every 8–12 hours for 3–4 weeks.
Second-generation rodenticide poisoning: starting dose 5 mg/kg subcutaneously or intramuscularly, then 2.5 mg/kg subcutaneously every 12 hours for 3 weeks, then reassess coagulation status.
Unknown rodenticide or indandione poisoning: starting dose 2.5–5 mg/kg subcutaneously or intramuscularly, then 2.5 mg/kg orally in divided doses every 8–12 hours for 3–4 weeks.
Cats:
First-generation rodenticide poisoning or K1 deficiency: starting dose 2.5 mg/kg subcutaneously or intramuscularly, then 1–2.5 mg/kg orally in divided doses every 8–12 hours for 5–7 days.
Second-generation rodenticide poisoning: starting dose 5 mg/kg subcutaneously or intramuscularly, then 2.5 mg/kg subcutaneously every 12 hours for 3 weeks, then reassess coagulation status.
Unknown rodenticide or indandione poisoning: starting dose 2.5–5 mg/kg subcutaneously or intramuscularly, then 2.5 mg/kg orally in divided doses every 8–12 hours for 3–4 weeks.
Second-generation rodenticide poisoning: starting dose 5 mg/kg subcutaneously or intramuscularly, then 2.5 mg/kg subcutaneously every 12 hours for 3 weeks, then reassess coagulation status.
Unknown rodenticide or indandione poisoning: starting dose 2.5–5 mg/kg subcutaneously or intramuscularly, then 2.5 mg/kg orally in divided doses every 8–12 hours for 3–4 weeks.
Calculate medication dosage for pets
Vitamin K1 (Phytonadione, Phytomenadione) (Mephyton, Aquamephyton) dosage calculation
Accurate dosing is essential when treating pets. To calculate a single dose correctly, you need three key values: the animal’s weight, the required dose of the active ingredient, and the concentration of the medication.
Calculation formula:
Single dose = (Animal weight × Required dose) ÷ Medication concentration
Important notes:
- Always consult a veterinarian before using any medication.
- Follow the recommended dosage and instructions for use.
Accurate dosing helps protect your pet’s health and reduces the risk of side effects.