Chlorambucil (Leukeran)
Dosage form:
Tablets 2 mg
Pharmacological group:
Alkylating agent
Therapeutic use:
Management of malignant neoplasms; lymphoproliferative and myeloproliferative diseases; immunosuppressive effect
Dosage:
Dogs:
1) Lymphoma: 15–20 mg/m² orally every 2 weeks + prednisolone, or 2–6 mg/m² every 24–48 hours.
2) Pemphigus (+ glucocorticosteroids): 0.1–0.2 mg/kg orally once every 24 hours initially, until clinical improvement. Then every other day, often long-term.
3) Other autoimmune diseases: 1–2 mg/m².
2) Pemphigus (+ glucocorticosteroids): 0.1–0.2 mg/kg orally once every 24 hours initially, until clinical improvement. Then every other day, often long-term.
3) Other autoimmune diseases: 1–2 mg/m².
Cats:
1) Autoimmune diseases: cats >4 kg — 2 mg per animal orally every 48 hours for 2–4 weeks, then reduce to minimum effective dose. Cats <4 kg — 2 mg per animal orally every 72 hours.
2) Pemphigus (+ glucocorticosteroids): 0.1–0.2 mg/kg orally once every 24 hours initially, until clinical improvement. Then every other day, often long-term.
2) Pemphigus (+ glucocorticosteroids): 0.1–0.2 mg/kg orally once every 24 hours initially, until clinical improvement. Then every other day, often long-term.
Calculate medication dosage for pets
Chlorambucil (Leukeran) dosage calculation
Accurate dosing is essential when treating pets. To calculate a single dose correctly, you need three key values: the animal’s weight, the required dose of the active ingredient, and the concentration of the medication.
Calculation formula:
Single dose = (Animal weight × Required dose) ÷ Medication concentration
Important notes:
- Always consult a veterinarian before using any medication.
- Follow the recommended dosage and instructions for use.
Accurate dosing helps protect your pet’s health and reduces the risk of side effects.